Speaking to The Daily Beast, Scott said that the science fiction movie is in the early stages of development.
"Funny enough, I started my first meetings on the Blade Runner sequel last week," he said. "We have a very good take on it. And we'll definitely be featuring a female protagonist."
Hampton Fancher, who was co-writer of the original Blade Runner movie with David Webb Peoples, is in talks to reunite with Scott on the follow-up.
Producers also revealed that the movie will be a sequel, with the story taking place "some years after the first film concluded".
Blade Runner starred Harrison Ford as Rick Deckard, a police officer on the hunt for bioengineered beings known as replicants. The film performed poorly at the box office on its original release but has since gone on to achieve cult classic status.
The film is based on Philip K Dick's novel Do Androids Dream of Electric Sheep?
Watch Rutger Hauer's 'tears in the rain' speech from the original Blade Runner movie below: