Ridley Scott's Blade Runner took the top spot, with The Empire Strikes Back, Aliens, Star Wars and Lord of the Rings: The Fellowship of the Ring rounding out the top five.
The results were taken from over 10,000 votes.
SFX editor Russell Lewin praised Blade Runner's "remarkable climb in popularity" following its initially poor critical and commercial reception.
"This was a film that was both a commercial and critical failure when it was released in 1982," Lewin said. "Since then, its reputation has slowly grown and grown. And no wonder - Ridley Scott's film is a striking work.
"Full of ambiguity, with complex and fascinating themes, it has stunning visuals that have been influencing sci-fi movies ever since, and rewards the viewer the more they watch it."
He continued: "To hold off the likes of the first two Star Wars films, Alien and Aliens and The Lord of the Rings films is an incredible achievement.
"SFX congratulates Blade Runner and Ridley Scott on this fantastic result!"
It was announced last week that the upcoming sequel to Blade Runner will take place some years after the first film and will feature a female protagonist.
SFX's top 10 list is as follows:
1. Blade Runner
2. The Empire Strikes Back
4. Star Wars
5. The Lord of the Rings: The Fellowship of the Ring
6. The Matrix
9. Back to the Future
10. The Dark Knight
Watch the trailer for Scott's upcoming film Prometheus below: