Films such as the Harry Potter series, both Guy Ritchie's Sherlock Holmes films, The Dark Knight and Inception have been filmed in the historic Leavesden Studios, which Warner officially purchased in 2010.
After a £99 million ($155m) revamp the studios have reopened, making Warner Bros the only Hollywood film studio with a permanent base in the UK, states The Hollywood Reporter.
The 250,000 square foot space, situated 18 miles from central London, houses nine stages, a 100-acre back-lot, and one of the largest heated underwater filming tanks in Europe.
It also houses the recently-opened Making of Harry Potter Warner Bros studio tour.
"The opening of Warner Bros Studios Leavesden clearly demonstrates the company's commitment to the UK, and underlines our belief in the world-class talent that resides on these shores," said Josh Berger, president and managing director of Warner Bros Entertainment for the UK, Ireland and Spain.
"This significant infrastructure outlay - probably the single biggest the UK film industry has witnessed in decades - will further amplify the UK's reputation as the go-to place for film and TV production."
Warner reportedly plans to use the studios to make several of its own films per year, but will also allow other productions to use the space.
"Back in 2000, we produced just one movie here in the UK - last year it was seven," said Warner executive VP and managing director Roy Button. "By adding this important resource to the UK's studio landscape we are helping to meet not just our own production needs, but those of the wider thriving British film industry."
Thanks in large part to the popularity of the Harry Potter series, Warner retained its spot as the biggest-grossing studio in the UK for the second consecutive year in 2011.
Watch a trailer for Warner's upcoming The Dark Knight Rises below: