The Hangover star will play a love interest to Amy Poehler in They Came Together and will cameo in We're the Millers, reports Deadline.
They Came Together tells the story of a local business owner (Poehler) whose store is being shut down by a corporate development.
Helms will play accountant Eggbert, whose rival for Poehler's character's affections comes in the form of a corporate businessman being played by Paul Rudd.
We're the Millers focuses on a pot dealer (Jason Sudekis) who makes up a fake family as part of his plan to bring weed into the US from Mexico.
Helms will play the boss of Sudekis's character who also has his own secrets.
Helms will make his return to The Office when it premieres on Thursday, September 20 on NBC.
Watch the trailer for The Hangover Part II below: