From American History X director Tony Kaye, the drama stars Adrien Brody as Henry Barthes, a substitute teacher who drifts through his assignments without forming any kind of attachment to his students or colleagues.
Detachment's supporting cast includes Mad Men star Christina Hendricks, Bryan Cranston, Lucy Liu and Oscar-winner Marcia Gay Harden.
The film is Kaye's first major release since his critically-acclaimed debut in 1998 with American History X. His next project, titled Attachment, is a sexually-charged thriller starring Harry Potter's Tom Felton and Sharon Stone.
Detachment opens in UK cinemas on July 13.
Photo gallery - Detachment in pictures: