The Hurt Locker actor is reportedly in line to play the Falcon in the Captain America: The First Avenger sequel, says The Hollywood Reporter.
The plot details for the next instalment are currently not known, but the title points towards a story following Captain America's resurrected sidekick Bucky as a brain-washed assassin known as the Winter Solider.
Mackie would play Sam Wilson, a Harlem-based character who joined Captain America in the 1970s as his partner. He has a suit that allows him to fly and improve his strength, while he can also telepathically talk to birds.
The film will arrive at cinemas on April 4, 2014.
Anthony Mackie can currently be seen in Abraham Lincoln: Vampire Hunter, while he has also recently starred in The Adjustment Bureau, Real Steel and Man on a Ledge.
He recently expressed an interest in starring in the rumoured Black Panther movie.