Around 250 people will work on the evening shoots for the latest instalment of the action series in late August and early September.
However, none of the main cast - including Vin Diesel, Dwayne Johnson or Paul Walker - will be present at the time.
Glasgow was chosen by the movie's producers after a meeting earlier this year with the city's Film Office.
The scenes will shoot in Cadogan Street and Broomielaw, reports BBC News.
Glasgow City Council leader Gordon Matheson said: "It is great to see the city attracting another movie of this size so soon after our marvellous success in 2011.
"We look forward to seeing the Fast 6 shoots here and giving them a great Glasgow welcome."
Glasgow Film Office has stated that recent Hollywood productions - including Brad Pitt's World War Z - have increased the city's economy by £20.15m.
Other movies shot in the city include Tom Hanks's Cloud Atlas, Scarlett Johansson's Under the Skin and David Tennant's The Decoy Bride.
A sixth and seventh movie in the Fast & Furious series were confirmed by Vin Diesel last December.
The film was previously rumoured to be shooting some scenes in Southend-on-Sea.
Similar to the previous movie, the project will be known as Fast Six.