The Die Hard star is being lined up to play covert operative Mitch Rapp in Jeffrey Nachmanoff's adaptation of Vince Flynn's novel, Variety reports.
American Assassin follows CIA agent Rapp as he embarks on a revenge mission. The character has appeared in multiple Flynn novels, including Consent to Kill, which CBS is also adapting.
Edward Zwick adapted the screenplay alongside Last Samurai scribe Marshall Herskovitz. Zwick was originally attached to direct before opting to helm The Great Wall instead.
Lorenzo di Bonaventura and Nick Wechsler are attached to produce the project.
Willis will next appear in cinemas in Looper, scheduled to arrive on September 28.
Watch a trailer for Looper below: