The couple married in June 2009, having met on the set of 2006 film Step Up.
The pair play Jake and Jess in upcoming film 10 Years, and Channing revealed that he enjoyed every minute he got to work with his wife.
When the star was asked by US OK magazine why his wife is the perfect co-star, he replied: "Because she's my loved one. She's my baby. I mean, I'm with her all the time, might as well just turn the cameras on."
Dewan admitted that the pair find it so easy to act together as they are a couple in real life.
"I guess it was easy," she said. "We're playing a couple that has been together for quite some years, playing a boyfriend and girlfriend that have been together for a while, that chemistry was obviously already there.
"We have a very playful energy together in real life and I think we sort of just injected that into Jake and Jess and we didn't put too much pressure on it, to be honest."
Watch the trailer for 10 Years below: