The David O Russell-helmed drama stars Cooper as a man recently released from a psychiatric institution, who develops a relationship with a similarly troubled neighbour (Lawrence).
O Russell also penned the script, which is adapted from Matthew Quick's 2008 novel of the same name.
Robert De Niro, Jacki Weaver, Julia Stiles and Chris Tucker round out the supporting cast of The Silver Linings Playbook, which won the 'People's Choice Award' at this year's Toronto Film Festival.
Cooper and Lawrence will also be co-stars in Susanne Bier's upcoming Depression-era drama Serena.
Watch Jennifer Lawrence speaking to Digital Spy about her role in The Hunger Games below: