Beyoncé, Colin Farrell, Amanda Seyfried, Johnny Knoxville and Josh Hutcherson are among the voice talent of the upcoming animated project.
Epic centres around a teenage girl who is transported to a secret world, and has to team up with a group of characters to save both the real and fantasy worlds.
Christoph Waltz, Jason Sudeikis, Pitbull, Steven Tyler, Aziz Ansari, Blake Anderson and Judah Friedlander will also be among the all-star cast in the film.
The picture comes from Blue Sky Studios, the team behind the Ice Age movies and Rio among others.
The project is directed by Ice Age's Chris Wedge, with a script from Daniel Shere.
The film will be released in 3D on May 24, 2013 in the UK and US.