The actress will reprise her role as Gwen Stacy opposite Andrew Garfield's Peter Parker in Marc Webb's upcoming sequel, which begins filming next week.
"This next script is so great," Stone told Hitfix. "It's overwhelming, though, to think that next week it begins. It's just so crazy.
"So I am really excited, but I'm just like, 'Oh my God, here we go!'"
Webb will direct two sequels to last year's reboot, with Shailene Woodley (The Descendants) confirmed to take on the role of Mary Jane Watson, as played by Kirsten Dunst in Sam Raimi's trilogy.
Chronicle star Dane DeHaan will play Peter Parker's best friend Harry Osborn, who was portrayed by James Franco in the original films.
Meanwhile, Jamie Foxx will play the villainous Electro.
Watch Digital Spy interview the cast of The Amazing Spider-Man below: