The actress - who plays M in the latest James Bond movie - spoke of her surprise that the film was snubbed in the main categories.
"I'm very, very sorry that nothing has been recognised," she told BBC Radio 4.
"That's a great pity. I thought Sam Mendes directed it absolutely beautifully. It was a terrific film."
Skyfall has been nominated for five prizes at the 2013 Oscars, but mainly for technical prizes including cinematography, sound editing and sound mixing.
> Skyfall BAFTA snub: Did Daniel Craig, Sam Mendes deserve nominations?
Adele's theme song 'Skyfall' has also been recognised in the 'Best Original Song' category.
When asked if she felt there was a bias against Bond films, she said: "There may be. I don't know. I hope not.
"I just think that all round it was really wonderfully directed and presented and filmed and lit and shot.
"But I've got a BAFTA nomination and that's terrific. I think it's good luck if you get an Oscar nomination and bad luck if you don't."
Skyfall was nominated for eight BAFTA prizes, including 'Best Supporting Actress' for Dench and 'Best Supporting Actor' for Javier Bardem.
James Bond will be given a special tribute at the ceremony to celebrate its 50th anniversary.
The 85th Academy Awards will take place in Los Angeles on February 24, and will be hosted by Family Guy creator Seth MacFarlane.
Oscars 2013 - Nominations in pictures: