The 14-second spot features snapshots of Iron Man down and out in the snow, Tony Stark's home coming under attack and Don Cheadle's James Rhodes unmasked as the Iron Patriot.
Iron Man 3, directed by Shane Black, sees Stark (Robert Downey Jr) face the villainous Mandarin (Ben Kingsley) as he searches for those responsible for an attack on his personal world.
Gwyneth Paltrow returns as Pepper Potts, while Rebecca Hall (as Maya Hansen), Guy Pearce (Aldrich Killian) and James Badge Dale (Eric Savin) are new cast additions.
A new poster for the film, showing Stark plummeting from the sky in his superhero armour, has also been released through the Iron Man Facebook page.
Iron Man 3 will open in cinemas on April 26.
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