The former Office star's casting was revealed in an image released by director Marc Webb, who hinted that the actor is playing an Oscorp employee.
"Day 38. A supposed rumour about a Dunder-Mifflin takeover of Oscorp?" Webb teased on Twitter.
Andrew Garfield and Emma Stone lead the cast for The Amazing Spider-Man 2, reprising their roles as Peter Parker and Gwen Stacy respectively.
The villains for Webb's sequel include Oscar winner Jamie Foxx as Electro and Golden Globe recipient Paul Giamatti as Rhino.
Shailene Woodley joins the Spider-Man franchise as Mary Jane Watson in the new film, while Chris Cooper and Dane DeHaan are playing father and son Norman Osborn and Harry Osborn.
Norman Osborn has been portrayed in the Spider-Man comics and in previous films as the devious owner of Oscorp, who would late transform into classic villain the Green Goblin.
The Amazing Spider-Man 2 opens on April 18, 2014 in the UK and on May 2, 2014 in the US.
Watch Digital Spy interview the cast of The Amazing Spider-Man below: