The trailer's premiere will be followed by a live chat with the film's director Neil Burger and various YouTube talent and fans.
The event will be live streamed here on Wednesday from 8.30am PT (4.30pm GMT).
Five new character posters have also been unveiled, featuring Tori (Maggie Q), Max (Mekhi Phifer), Eric (Jai Courtney), Christina (Zoe Kravitz) and Peter (Miles Teller).
Stars Shailene Woodley and Theo James recently appeared in new posters for the dystopian drama.
Woodley plays Tris Prior, a 'Divergent' who is unable to fit into any one group in a future world formed of distinct factions based on personality.
She is forced to act when she uncovers a conspiracy to destroy all Divergents. James takes on the character of Four, Tris's trainer who transfers her between the factions.
Kate Winslet also stars as Jeanine Matthews in the adaptation of Veronica Roth's best-selling novel
Divergent is scheduled for release on March 21 in the US and April 4 in the UK. Watch a preview below: