The director's latest film with Leonardo DiCaprio, a sex and drugs-fuelled account of Jordan Belfort's rise to riches on Wall Street, was met with some disdain by senior Oscar voters at an Academy screening at the Samuel Goldwyn Theatre in Los Angeles.
Hope Holiday, who appeared in Billy Wilder's comedy classic The Apartment, voiced her disapproval of the film's portrayal of Wall Street excess and claimed that one screenwriter verbally attacked Scorsese after the post-screening Q&A.
Holiday wrote in a Facebook update: "Last night was torture at the Academy - The Wolf of Wall Street - three hours of torture.
"Same disgusting crap over and over again - after the film they had a discussion which a lot of us did not stay for.
"The elevator doors opened and Leonardo DiCaprio and Martin Scorsese and a few others got out. Then a screenwriter ran over to them and started screaming, 'Shame on you'. Disgusting."
The Wolf of Wall Street recently scored two Golden Globes nominations and is expected to be in the mix for BAFTAs and Oscars in 2014.
It will open on Christmas Day in the US and January 17 in the UK. Watch the trailer below: