The footage shows 'international tour manager' Dominic Badguy (Ricky Gervais) telling Muppets including Kermit, Miss Piggy and Fozzie Bear that he can help them capitalise on their 'hot moment'.
Muppets Most Wanted Super Bowl advert debuts - watch video
The sequel to 2011's The Muppets follows the titular characters on a sold-out global tour, but also caught up in the plot of a group of international criminals led by Constantine - who looks uncannily like Kermit - and his second-in-command played by Gervais.
Tina Fey, Tom Hiddleston, Salma Hayek, Stanley Tucci, Christoph Waltz, Danny Trejo, Lady Gaga and P Diddy feature in the movie as well.
Gervais recently spoke to Digital Spy about the film's choreography, saying: "I am doing a song-and-dance number. It's a big Hollywood song and dance, me and the frog.
"There's tap dancing and up-and-down stairs. I'm a pretty good singer - I rate myself at singing. Dancing? I'm your dad at a party."
Muppets Most Wanted will be released in US cinemas on March 21 and in the UK on March 28.
Watch Digital Spy's Muppets Most Wanted set visit below: