Samantha Morton, Aaron Paul and Helen Hunt star in writer-director Steven Bernstein's breast cancer drama.
The film is based on the true story of geneticist Mary Claire King (Hunt), who discovered a genetic link to breast cancer.
Morton plays cancer survivor Parker, who becomes involved in the attempt to better understand the disease.
Bradley Whitford, Rashida Jones, Richard Schiff, Alice Eve, Maggie Grace, Marley Shelton, Chris Mulkey and Corey Stoll also feature in the film.
The movie is cinematographer Bernstein's feature directorial debut.
Decoding Annie Parker will arrive in US cinemas on May 2. A UK release date is yet to be confirmed.