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Talking about his World War II drama Miracle At St. Anna at Cannes, the filmmaker said he is one of the few directors in the business to depict death in a sensitive way.
He said: "I always treat life and death with respect, but most people don't. Look, I love the Coen brothers; we all studied at NYU. But they treat life like a joke. Ha ha ha. A joke.
"It's like, 'Look how they killed that guy! Look how blood squirts out the side of his head!' I see things different than that."
Lee also criticised Eastwood for the lack of black actors in his movies, saying: "[He] made two films about Iwo Jima that ran for more than four hours total, and there was not one Negro actor on the screen.
"If you reporters had any balls, you'd ask him why. There's no way I know why he did that - that was his vision, not mine. But I know it was pointed out to him and that he could have changed it. It's not like he didn't know."
Miracle At St. Anna is scheduled for release in October.
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