The double A-side single will feature 'Do Ya' from the band's latest album Radio:ACTIVE along with a cover of Rod Stewart's 'Stay With Me'.
The group will appear on the November 14 Children In Need broadcast, with the track available digitally on November 23 and in the shops a day later. All proceeds will go to charity.
"We're so honoured to be releasing the official single for Children In Need. We've performed several times on the live show in the past and it's always been an amazing night with a fantastic atmosphere," said band member Tom Fletcher.
"Hopefully our single can help raise more money than ever for what is such a great cause."