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The pair, each nominated for Grammy Awards this year, are keen to record a song together.
Both artists are currently working on their new albums and Estelle has said that working with the 'Chasing Pavements' singer would be "dope".
"I'm really excited to start working on my next album," she told The Sun. "I'm going to go totally left field and surprise a lot of people.
"I'm going to hit it out the ball park with this one. I’m thinking a mix of Coldplay and Marvin Gaye."
Adele is reportedly also planning a duet with former X Factor contestant Laura White.
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