The event, which has been planned for the Southbank Centre in Lambeth, will feature comedian Marcus Brigstocke, American singer-songwriter Vanessa Carlton and former So Solid Crew rapper Asher D, according to PA.
Beatbox artist Shlomo dreamed up the concert in a move to help young people steer clear of crime and has gained the backing of London Mayor Boris Johnson.
Shlomo said: "I really believe that beatboxing and music in general gives us the potential to inspire a change, to move away from the despondent attitudes that have led to problems with postcode wars, drugs, knives and gun crime.
"Working creatively with young people gives them an opportunity to take an interest in their own development. Suddenly it can be considered cool to apply yourself to something."