The guitarist admitted that a reformation is more likely following singer Marie Fredriksson's successful treatment for a brain tumour in 2002.
"We've talked about it. It's really up to Marie. She's started doing a few concerts before Christmas as a guest artist in Sweden, which was a big success for her, so slowly but surely she's coming back to the stage," he told the BBC.
"I would love to do more Roxette and I would love to do more recordings as well, because she's a great person and a great singer, but I don't want to push her at all.
"It's really up to her. If she calls me up and tells me I'm ready, I'd say let's go for it."
Roxette rose to fame in the late 1980s with their US number one single 'The Look'. They enjoyed five Top 10 UK albums during the 1990s.
Gessle plays a solo show at the O2 Academy Islington in London on May 4.