Stryder and the hip-hop collective are currently at the top of the UK singles chart with their collaboration 'Number One'.
Also joining the Hyde Park event's bill are Lady Sovereign, Chipmunk, The Black and White Years and Steve Appleton.
The Sunday will be headlined by Kanye West, while Q-Tip, Flo Rida, Kid Cudi and Daniel Merriweather are also confirmed to perform.
Joining Basement Jaxx and The Streets on the Saturday are Metric, Skint & Demoralised, Master Shortie, The Japanese Popstars, and The Phenomenal Handclap Band.
Tickets for both days are still available.