Curated by Simpsons creator Matt Groening, the event takes place at Butlins, Minehead from May 7 to May 9.
Spiritualized will play their 1997 album Ladies and Gentlemen We Are Floating in Space in full and are joined on the lineup by Hope Sandoval & The Warm Inventions, Cold Cave, The Tiger Lillies, The Fresh And Onlys and Hello Saferide.
Bands already confirmed for the festival include Iggy & The Stooges, The xx, James Chance and Les Contortions, Boredoms, The Residents, Shonen Knife and Viv Albertine's Limerence.
