The track, which topped the UK charts in November, will be reworked to include a shout-out to producer JR Rotem at the start.
"We're going to put out 'Everybody In Love' as the first one in the US. It starts off with JR giving a shout out to himself," Marvin Humes told the Daily Star.
"Initially we asked for it to be changed to JLS instead of JR, but we lost that battle.
"Now we are so glad we kept it as he's had such huge success, with Jason Derulo and Iyaz both going to No.1 with tracks he's produced."
Humes added that the group are still concentrating more on their UK fans than breaking into the US market.
"We're not making a big deal about cracking America - it's still all about the UK. We'll see how things go," he said.
JLS are currently on their first headline UK tour and will perform their debut single 'Beat Again' at the Brit Awards in London tomorrow night.