Florence Welch's band has been nominated for 'Breakthrough Act', 'Best Album', 'Best Live Act' and 'Song Of The Year' for 'You've Got The Love', according to the BBC.
Kasabian are up for three prizes, under 'Best Live Act', 'Song Of The Year' for 'Fire' and 'Best Album' for 'West Ryder Pauper Lunatic Asylum'.
Richard Hawley and the Arctic Monkeys have two nominations each, with both nominated for 'Best Song', for 'Open Up Your Door' and 'Crying Lightning', respectively.
Hawkwind are to receive the 2010 'Mojo Maverick' award.
"Despite the fact that they have rarely flirted with the mainstream, their music and their attitude has inspired so many different areas of modern music," said Mojo's editor-in-chief, Phil Alexander.
The winners will be voted for by readers of Mojo magazine, and will be revealed in a ceremony on June 10 in London.