Their hit collaboration - the second single from Eminem's Recovery album - climbed to number two on yesterday's UK singles chart behind Aussie dance smash 'We No Speak Americano'. It is also top of the US and Irish countdowns at present.
Behind Eminem and Rihanna, Enrique Iglesias holds steady at two with 'I Like It', while Katy Perry remains at three with former chart-topper 'California Gurls'.
Meanwhile, Adam Lambert's 'If I Had You' zooms from eight to four, matching the peak of his previous Aussie single, 'Whataya Want From Me'.
The highest new entry of the week comes from Newton Faulkner, who bows at eight with 'I Hate Mondays'.
Usher also debuts inside the top ten this week, landing at ten with Pitbull collaboration 'DJ Got Us Fallin' In Love'.
The top ten singles in full (click where possible for our reviews):
1. (1) Eminem ft. Rihanna: 'Love The Way You Lie'
2. (2) Enrique Iglesias ft. Pitbull: 'I Like It'
3. (3) Katy Perry ft. Snoop Dogg: 'California Gurls'
4. (8) Adam Lambert: 'If I Had You'
5. (4) B.o.B. ft. Hayley Williams: 'Airplanes'
6. (5) Travie McCoy ft. Bruno Mars: 'Billionaire'
7. (6) Uncle Kracker: 'Smile'
8. (-) Newton Faulkner: 'I Hate Mondays'
9. (10) Eminem: 'Not Afraid'
10. (-) Usher ft. Pitbull: 'DJ Got Us Fallin' In Love'