The 'Crazy Train' singer is lined up to perform in Tel Aviv on Tuesday as part of the annual Ozzfest concert series.
In recent months, artists such as Elvis Costello, Klaxons and The Pixies have axed scheduled performances in the country due to Israel's May 31 seizure of an aid flotilla bound for Gaza, according to AFP.
Ozzy told reporters that he wished to avoid discussing whether his visit to the war-torn country would cause controversy because "I wouldn't know what I was talking about".
His wife Sharon dismissed potential condemnation of her husband's decision to hold a concert in the region. She said: "Britain has the IRA (Irish Republican Army) and no-one cancels concerts there."
When questioned as to why he had never visited Israel before, Ozzy responded by saying: "I don't know, I was drunk for years."