Science & Faith, the band's second album, knocked Phil Collins off the top spot following a brief fall to number two last week.
Elsewhere on the chart, Mark Ronson & The Business Intl debuted at number two with Record Collection, while KT Tunstall entered the chart at number five with her third album Tiger Suit.
Simply Red re-entered the chart at number nine with 25 - The Greatest Hits after last Saturday's ITV1 special Simply Red: For The Last Time.
Other new entries include Le Noise by Neil Young at number 18 and Jimmy Eat World with Invented at number 29.
The Top 10 in full:
1. (2) The Script: 'Science & Faith'
2. (-) Mark Ronson & The Business lntl: 'Record Collection'
3. (1) Phil Collins: 'Going Back'
4. (-) Central Band Of The RAF: 'Reach For The Skies'
5. (-) KT Tunstall: 'Tiger Suit'
6. (9) Mumford & Sons: 'Sigh No More'
7. (-) Eric Clapton: 'Clapton'
8. (4) Brandon Flowers: 'Flamingo'
9. (-) Simply Red: '25 - The Greatest Hits'
10. (8) Katy Perry: 'Teenage Dream'
Source: Official Charts Company
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