CNN reports that the facility's founder Rodolfo Vazquez has put a selection of his 8,500 Beatles-related items on display in Buenos Aires' cultural complex The Plaza.
Vazquez, who holds the Guinness World Record for owning the most Beatles memorabilia, explained that he began collecting rare items after first hearing the Rubber Soul LP at age 10.
"What I did was collect things, collect and collect like any fan, of football, stamps, action figures, whatever - the little bit that I could get because in Buenos Aires there wasn't a lot of material," he said.
Besides a series of exhibits on the band's history, the museum also houses a Beatles-themed restaurant and a replica of Liverpool's Cavern Club where John Lennon, Paul McCartney, Ringo Starr and George Harrison first performed together.
The Beatles released nearly two-dozen platinum-selling LPs and more than 25 US top ten singles before splitting in 1970.