Aguilera, who sang the US national anthem at last Sunday's Super Bowl, is said to have been booked for the ceremony with singer and actress Jennifer Hudson.
Industry blog Wayne's World reports that the pair will pay homage to Aretha Franklin, who recently underwent surgery for a mystery illness, at the start of the event.
Performers confirmed for this year's Grammys include Justin Bieber, Katy Perry, Rihanna, Eminem, Nicki Minaj and Lady GaGa, who will give her first live performance of new single 'Born This Way'.
Aguilera recently apologised for fluffing a line during her Super Bowl appearance.
The Grammys take place on February 13 at Los Angeles' Staples Centre and will be broadcast on CBS.