'Born This Way' debuts at number one in the singles chart, ahead of Jedward who chart at number two with their track 'Lipstick' - the song which they will perform at Eurovision to represent Ireland. Jessie J falls two to number three.
Following her highly-praised performance at the Brit Awards, Adele's 'Someone Like You' leaps 17 places into ninth position. Meanwhile, JLS's new single 'Eyes Wide Shut', which features Tinie Tempah, climbs 24 spots to number 14.
Notable climbers this week include Dr Dre's 'I Need A Doctor' at 30, Nicki Minaj and Drake's 'Moment 4 Life' at 37 and a new entry from Justin Bieber and Jaden Smith at number 40 with 'Never Say Never'.
This week's top 10 in full:
1. (*) Lady GaGa: 'Born This Way'
2. (*) Jedward: 'Lipstick'
3. (1) Jessie J ft. B.O.B : 'Price Tag'
4. (3) Rihanna: 'S&M'
5. (5) Adele: 'Rolling In The Deep'
6. (2) Bruno Mars: 'Grenade'
7. (6) Martin Solveig & Dragonette: 'Hello'
8. (9) Enrique ft. Ludacris: 'Tonight I'm Loving You'
9. (26) Adele: 'Someone Like You'
10. (7) Diddy Dirty Money: 'Coming Home'