Luke Bryan and the Judds will also take to the stage during the Las Vegas event, it has been announced.
They join previously-announced presenters including Water for Elephants co-stars Reese Witherspoon and Robert Pattinson, Julianne Hough, Ryan Seacrest, Chris Young and teen surfer Bethany Hamilton.
Performances will come from artists including Carrie Underwood, Rihanna and Jennifer Nettles, and all six 'Entertainer of the Year' nominees - Jason Aldean, Toby Keith, Miranda Lambert, Brad Paisley, Taylor Swift and Keith Urban.
Darius Rucker will also take to the stage alongside campers from the ACM Lifting Lives programme to perform an original song called 'Music from the Heart'.
The 46th annual Academy of Country Music Awards air live from Las Vegas on Sunday, April 3 from 8pm ET/PT on CBS.
> In Full: ACM Awards 2011 - Nominees