The LP, which has already become the fastest-selling of 2011 worldwide, continues to hold former chart-topper Adele in second and third position with her 21 and 19 collections respectively.
This week's highest new entry is another showing for the cast of Glee. whose latest collection of tracks from the show debuts at number four. Meanwhile, Bell X1 enjoy a 13-place jump into the Top 10 with Bloodless Coup.
Gemma Hayes charts at number 11 with Let It Break, while Aloe Blacc enjoys a huge 73-spot rise to number 16 with Good Things.
Other new entries to hit the chart this week include Seasick Steve's You Can't Teach An Old Dog New Tricks at number 18, Death Cab For Cutie's Codes and Keys at 23, Neil Diamond's Greatest Hits: The Collection 1966-1992 at number 35 and Andrea Corr's Lifelines at number 40.
Cee Lo Green is among the notable climbers this week. The Lady Killer jumps 26 spots to number 21, while Take That's Progress sits at 30 as they round off week one of their record-breaking tour.
This week's Top 10 albums in full:
1. (1) Lady GaGa: 'Born This Way'
2. (2) Adele: '21'
3. (3) Adele: '19'
4. (-) Glee Cast: 'Glee: The Music: Vol. 6'
5. (4) Ryan Sheridan: 'The Day You Live Forever'
6. (6) Thin Lizzy: 'Waiting For An Alibi: The Collection'
7. (7) Bruno Mars: 'Doo Wops & Hooligans'
8. (5) Kings of Leon: 'Come Around Sundown'
9. (11) Lady GaGa: 'The Fame'
10. (23) Bell X1: 'Bloodless Coup'
> Pitbull's 'Give Me Everything' tops Irish chart
Watch Lady GaGa perform new single 'The Edge of Glory' on the American Idol final below: