The 'Run The World (Girls)' singer was boosted to pole position following her phenomenally well-received headline slot at last weekend's Glastonbury festival.
4 is Beyoncé's second number one solo LP after her debut Dangerously In Love, which topped the rankings in 2003. She previously reached the peak of the album chart in 2001 with her former girl group Destiny's Child and their third studio record Survivor.
The 29-year-old has also seen her 2008 album I Am...Sasha Fierce shoot to 38 from last week's 127 off the back of her Glastonbury performance.
Beyoncé's arrival pushes former chart champions Born This Way by Lady GaGa and Progress by Take That down to three and four, where they become sandwiched between Adele's 21 and 19 records at two and five respectively.
The so-called "Glastonbury effect" continues outside the top five with Jessie J racing from 11 to six with Who You Are, as her fellow performers Biffy Clyro and Kaiser Chiefs score new entries with Revolutions/Live At Wembley and The Future Is Medieval at nine and ten.
Also reaping the rewards of an appearance at the legendary event are Chase & Status and Cee Lo Green, who shoot five and six places respectively to 12 and 13 with No More Idols and The Lady Killer, while Stevie Nicks enters just behind them at 14 with her seventh studio album In Your Dreams.
By contrast, Bon Iver's self-titled LP and Suck It And See by the Arctic Monkeys both fall to the double digits, after dropping 11 and ten places to 15 and 16, an inch ahead of Mumford & Sons and Noah & The Whale, the final two Glastonbury performers in this week's top 20.
The 'Little Lion Man' singers are up nine spots to 17 with Sigh No More, while Noah And The Whale finish in 20th place after settling at 29 last Sunday.
The Top 10 in full:
1. (-) Beyoncé: '4'
2. (2) Adele: '21'
3. (1) Lady GaGa: 'Born This Way'
4. (3) Take That: 'Progress'
5. (-) Adele: '19'
6. (11) Jessie J: 'Who You Are'
7. (7) Caro Emerald: 'Deleted Scenes From The Cutting Room Floor'
8. (8) Bruno Mars: 'Doo Wops & Hooligans'
9. (-) Biffy Clyro: 'Revolutions/Live At Wembley'
10. (-) Kaiser Chiefs: 'The Future Is Medieval'
Source: Official Charts Company
> This week's singles chart
Watch Beyoncé perform 'Run The World (Girls)' from her number one album 4 at Glastonbury below:
View the latest Official Top 100 Album Chart