The band will release the track on September 4, a week ahead of their new album Junk Of The Heart on September 12.
The Kooks' third studio album Junk Of The Heart will serve as the follow-up to 2008's Konk, which reached number one on the UK album chart upon its release.
The record was recorded in London and New York with producer Tony Hoffer, who has previously collaborated with Depeche Mode, The Fratellis and Supergrass.
Junk Of The Heart is the first album the band have recorded with new bassist Pete Denton, who joined after founding member Max Rafferty left in 2008.
The Kooks will follow the single and album's release with a UK headline tour this October.
Listen to 'Is It Me' below: