The producer, who worked on the single 'Cold Shoulder' from Adele's debut album 19, told the Evening Standard that he was impressed with her drive when they first met.
Ronson said: "She was 18, chain-smoking Marlboro Lights, and watching Jerry Springer. She said, 'This is the song I want you to produce'. I was struck by her determination."
He added: "With all the manufactured, computer-adulterated pop out there, it's great that when a person comes along with an incredible voice and real songs it still trumps everything.
"It's great for the music industry that it happened. And I love Adele as a friend, I think she's f**king amazing."
Asked if he could take any of the credit for her success, Ronson said: "I championed her early on but she didn't need me for her success; it was always going to happen. Sometimes the stars just line up and that's it."
Adele's second album 21 yesterday celebrated its 18th week at the top of the UK album chart, while the record also heads the world music chart.
Ronson this weekend called Amy Winehouse, who died on Saturday, his "musical soulmate".
Watch the video for Adele's Mark Ronson-produced single 'Cold Shoulder' below: