According to Sky News, the singer's body was discovered on Thursday night at a hotel in El Segundo, California.
No details surrounding the singer's cause of death have been revealed, although The Mirror quotes Captain John Kades of the LA County Coroner's Office as suggesting it "could be a drug overdose".
Williams rose to fame in the '80s and early '90s following the release of her albums Vesta and Vesta 4U.
The singer had several successful singles during this time including 'Congratulations', and 'Sweet, Sweet Love'.
Watch the video for Vesta Williams's 'Congratulations' below: