The band supported the Irish rockers during their record-breaking '360' world tour, but have confessed that the experience taught them nothing new.
Frontman Tom Meighan told The Sun: "I didn't take in anything supporting them - them gigs were horrible. Worst ever. U2 fans are cardboard cut-outs.
"Can you imagine supporting U2? Their fans are probably into one band and one album - Joshua Tree. I didn't learn anything 'cos that's just a f**king different level."
He continued: "It was amazing to watch and meet them, but I didn't learn anything apart from just get the f**k out."
Meighan compared the experience to performing to empty stadiums.
He added: "That's how it felt to us. We were the support, so it is what it is. I hate supporting bands. We're not a support band. So that's never gonna happen again."
Kasabian topped the UK album chart with their fifth studio album Velociraptor! this past weekend.
The band will embark on a 13-date UK arena tour at the end of the year.
> Kasabian's new album 'Velociraptor!' track-by-track - video
Watch the music video for Kasabian's current single 'Days Are Forgotten' below: