The frontman said that he wouldn't rule out a duet between the band and the 'Bad Romance' singer, and described her as "terrific".
"Anything's possible," he told LA Weekly. "She's terrific, and it's not improbable."
Kiss are expected to release their 20th studio album Monster in January.
The band's Gene Simmons married his long-term partner Shannon Tweed at the weekend.
> Lady GaGa, Tony Bennett unveil 'The Lady Is a Tramp' video
Watch the video for 'Heaven's on Fire' by Kiss below: