The track is a cover of Massive Attack's 'Teardrop' and features a host of UK hip-hop talent, organised by Take That's Gary Barlow and produced by Labrinth.
Tulisa Contostavlos and Ms Dynamite provide vocals for the chorus, while Chipmunk, Ed Sheeran, Wretch 32, Rizzle Kicks, Dot Rotten, Mz Bratt and Tinchy Stryder rap verses.
The video sees the stars performing the single in the recording studio, while clips of youngsters who have benefitted from the charity are interspersed throughout.
'Teardrop' will be released on November 13 with all profits made from the sales to be donated to Children In Need.
Barlow recently named his new music group for the project The Collective.
Children In Need's live appeal show will be broadcast live on November 18 from 7pm on BBC One.
> Labrinth teases Children In Need single: 'Egos were left at the door'
Watch the music video for The Collective's 'Teardrop' below: