The chart-topping artists will join previously-confirmed performers Coldplay, Jessie J and LMFAO at the ceremony on November 6.
However, Snow Patrol and Derulo will perform at an alternative location from the main stage at Belfast's Odyssey Arena. Instead they will play Belfast's City Hall, which will be aired directly to the arena and on MTV.
"We're really looking forward to performing for the EMAs at such a special location on home-turf. It's going to be a great night and a lot of fun," said Snow Patrol.
Derulo added: "This is my first EMA and it's an honour to be asked to perform as I've always been an MTV fan. I am also very excited to perform for my Irish fans and visit Belfast for the first time."
Red Hot Chili Peppers were the first act announced to play this year's show.
Selena Gomez is to be the night's host and will be offering Twitter updates and behind-the-scenes gossip throughout the ceremony.
Tickets for the City Hall event will be free and will be available from www.gotobelfast.com from 8am on October 16.
Nominees for the 2011 MTV EMAs include Adele, Lady GaGa, Bruno Mars and Justin Bieber.
The MTV EMAs 2011 air Sunday, November 6 on MTV.
> MTV EMA nominations 2011: In full
Watch the music video for Snow Patrol's 'Called Out In The Dark' below: