Anthony Addis revealed that the band already have "lots of material" for the record, and are planning to release it in October 2012.
The manager told Billboard that Muse are currently back in the studio to make the follow-up to The Resistance.
"They've now gone into the recording studio," he said. "The plan is to do it all in London. Hopefully, the album might come out October next year.
"They've written a lot of material already but you don't know how it's going to gel between them all. They write constantly. They write on the road, so before or after a gig they'll write nearly every night. It's a serious process, but you don't know how it's going to turn out until you start practising it together, because everybody's done it individually."
Muse concluded their headlining set at this year's Reading Festival by playing their Origin of Symmetry album in full for the last time.
Watch Muse perform 'Uprising' at Glastonbury below: