Aguilera and Maroon 5 will pair up for a performance of their hit 'Moves Like Jagger' for the gala, which will also see Kelly Clarkson and Mary J Blige take to the stage.
Katy Perry and 'Give Me Everything' rapper Pitbull were previously confirmed to be performing during the AMAs.
Adele leads this year's American Music Awards nominees, with nods in the 'Artist of the Year' and 'Favourite Album in Pop/Rock' categories.
Perry, Lady GaGa, LMFAO and Bruno Mars also received multiple nominations.
Online voting will determine this year's winners.
> Read the full list of this year's American Music Awards nominations
The 2011 American Music Awards will air live from the Nokia Theatre on Sunday, November 20 at 8/7c on ABC.
> Justin Bieber's next album expected summer 2012
> Kelly Clarkson: 'Stronger is first album my label have agreed on'
Watch Justin Bieber's new music video for 'Mistletoe' below: