The legendary rock star, 63, is currently touring the UK with his 'Halloween Night of Fear' gigs, and has been performing on stage since he was 16 in 1964.
The 'Poison' singer explained that he would only retire if he couldn't perform to the best of his capabilities, or if people stopped attending his concerts.
"If I got to the point where I couldn't physically get on stage or if we did a show and no tickets were sold, I'd say, 'OK, time to hang it up'," he told OK magazine.
"But I feel great and we sell out every show. I'm going to ride this horse for as long as I can!"
Cooper recently said that Lady GaGa is the female equivalent of himself.
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Watch the video for Alice Cooper's 'Poison' below: