The singer was due to perform a string of rescheduled gigs in the UK throughout November, but has been forced to cancel all live show plans to undergo surgery on her throat.
"It is with deep regret that Adele has been forced to cancel her remaining live dates and promotional appearances in 2011," a statement read.
"She is to undergo surgery to alleviate the current issues with her throat and a full recovery is expected. As a result, doctors have ordered her to rest her voice and completely recuperate before looking to schedule any work commitments.
"Ticket holders for all cancelled live dates will receive a refund from the point of purchase. We apologise for any inconvenience and disappointment caused, and appreciate your understanding during this time."
The cancelled dates are as follows:
November 7 – Wolverhampton, Civic Hall
November 8 – Wolverhampton, Civic Hall
November 10 – Blackpool, Empress Ballroom
November 12 – Bournemouth, BIC
November 14 – Cardiff, Motorpoint Arena
November 15 – Plymouth, Pavillions
Adele was previously forced to cancel her tour of the US arranged for this month after doctors told her she needed more time to recover from illness. She had been scheduled to play dates in New Jersey, North Carolina, Tennessee, Florida, Georgia and Texas across October.
The star recently announced plans to release a live album and DVD of her September concert at London's Royal Albert Hall on November 29.
> Adele: 'Smoking isn't destroying my voice, talking is'
Watch the music video for Adele's 'Someone Like You' below: