The singer revealed that it was the "best" way to end her successful year, describing the nominations as an "incredible achievement".
"Just home from New York," she wrote on her official blog: "That's my main excuse for not posting a message sooner, but I'm also completely and utterly lost for words.
"A couple days after finally being able to talk again I'm pretty speechless. Thank you so much to the academy for nominating this record for 6 Grammys!!!"
She continued: "This has been the best year as it is but to end 2011 with this incredible achievement and honour is beyond anything I can express.
"Thank you to every single person who has taken a shining to this record, for making it have such an impact, this record has taken on a life of its own thanks to you. I made the record and you've made it what it's become."
Adele is nominated for 'Record of the Year', 'Album of the Year', 'Best Pop Vocal Album' for 21, 'Song of the Year', 'Best Short Form Music Video' for 'Rolling In The Deep' and 'Best Solo Performance' for 'Someone Like You'.
> Adele's '21' becomes UK's biggest-selling album of 21st century
> Grammy Awards 2012: Major nominees
Watch the music video for Adele's 'Someone Like You' below: