The pair are seen dancing in a field in the clip, which was unveiled on YouTube this week.
The track serves as the lead single from BoB's second studio album of the same name, which is scheduled for release in March 2012.
The rapper's debut LP, The Adventures of Bobby Ray, topped the Billboard chart in April last year and peaked at number 17 in the UK.
The record included the number one single 'Nothin' on You' and worldwide hit 'Airplanes', which featured Paramore's Hayley Williams.
Earlier this year, the star described his forthcoming album as "a real special project", adding: "I still feel like I got more to put out, I got more to say."
> BoB: 'New album will surprise fans'
Watch BoB and Lil Wayne's 'Strange Clouds' music video below: